DISCOVERY OF SULFONE-RESISTANT DIHYDROPTEROATE SYNTHASE (DHPS) AS A TARGET ENZYME FOR KAEMPFEROL, A NATURAL FLAVANOID

Discovery of sulfone-resistant dihydropteroate synthase (DHPS) as a target enzyme for kaempferol, a natural flavanoid

Kaempferol is a ubiquitous flavonoid, found in various plants having a wide range of known pharmacological activities, including antioxidant, antiinflammatory, anticancer, antiallergic, antidiabetic, neuroprotective, cardioprotective and antimicrobial activities.Nonetheless various evidence suggest that kaempferol is also able to interact with many

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